Expo is a managed platform for developing React Native apps without dealing with native build systems (Xcode, Android Studio, CocoaPods, Gradle). You write React/TypeScript, and Expo's build service (EAS Build) generates production APKs and IPAs. Expo Go is a development app that lets you test your app on a physical phone instantly (no build needed). Expo SDK includes 50+ modules: Camera, Notifications, Maps, File system, Payments, etc. These cover 90% of app needs. For the other 10% (specialized hardware, custom native code), you eject to bare React Native.